UC San Diego Undergraduates Forge New Area of Bioinformatics

Undergraduate students from the University of California San Diego have forged a new area of bioinformatics that may improve genomic and proteomic annotations and unlock a collection of stubborn biological mysteries. Their work will be published in the July 2008 issue of the journal Genome Research. Video by Daniel Kane – Jacobs School of Engineering cse-ece-ucsd.blogspot.com
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Interview with bioinformatics researcher Dr. Atul Butte on how computers are giving us a deeper understanding of human disease. National Institute of General Medical Sciences www.nigms.nih.gov

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USQ – Australia: Bioinformatics Radiotherapy, Dr Jesus Lopez

USQ Bioinformatics Senior Lecturer, Dr Jesus Lopez, will lead a world first study that will look at genes and their responsiveness to radiotherapy in bladder cancer sufferers. The study will be undertaken from next year and is of great importance to bladder cancer patients worldwide. ‘When treating bladder cancer there are two types of treatment, radiotherapy and removing the bladder,’ Dr Lopez said. ‘About 45 percent of bladder cancer patients require radiotherapy or surgery and radiotherapy has a failure rate of 50 percent, while surgery (bladder removal) diminishes quality of life considerably. ‘What we want to do is use Bioinformatics to test patient’s genes and see if we can predict whether or not radiation will work and discover which genes are involved in tumour-death.’ Support for the research has come from abroad, with interested stakeholders in the UK keeping an eye on the results. ‘The project is in collaboration with Cancer Research UK, The University of Ulster and the University of Leicester,’ Dr Lopez said. ‘Patients used in the study will be from the UK, while we will use bioinformatics to analyse data here.’ Dr Lopez has also received backing from the Australian Research Council (ARC) for the study after receiving a Discovery Grant worth 0000. ‘These Discovery Grants are very competitive and are not only based on the project that you want to do but also on your background,’ he said. ‘It is a vote of confidence and if you get some promising results there

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